P21 Peptide 5mg Lyophilized Powder for Research Category (personal reference): Peptides

P21 (5mg)

€104.40

Categories: Core Peptides, Cognitive Enhancement Research Tags: CNTF Mimetic, Cognitive, In-vitro, Neurogenesis, Neuroprotective, P21, Peptide, Research, Scientific Study Brand: Core Peptides

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Essential P21 Peptide: Proven 5mg for Neuroprotective Research

⚠️ Research Use Only. This product is intended exclusively for in-vitro scientific research. It is not approved for human or animal consumption, clinical use, or therapeutic application.

1.Introduction to P21 Peptide

2.Product Details

3.Understanding P21: A Synthetic CNTF Mimetic

4.Mechanism of Action and Research Applications

5.About the Brand

6.Frequently Asked Questions (FAQ)

1. Introduction to P21 Peptide

P21 peptide, also identified as P021, is a synthetic peptide meticulously designed to mimic the activity of ciliary neurotrophic factor (CNTF) on the brain without eliciting an allergic response. This 5mg formulation provides a high-purity compound for in-vitro scientific research, allowing investigators to explore its unique neuroprotective and neurodegenerative activities in various animal models. Derived from active regions of CNTF, P21 represents a significant advancement in peptide research, offering a stable and potentially more effective tool for studying neural cell survival and differentiation.

2. Product Details

Attribute	Detail
Brand	[Brand Name – placeholder]
Size	5mg
Type	P21 Peptide
Form	Lyophilized powder
Purity	>99%
SKU	P-P21

3. Understanding P21: A Synthetic CNTF Mimetic

The P21 peptide is a synthetic compound engineered to emulate the beneficial effects of ciliary neurotrophic factor (CNTF), a protein known for promoting the survival and differentiation of various neural cells, including neurons and oligodendrocytes. CNTF has been suggested to exhibit possible neuroprotective and neurodegenerative activity in animal models of neurodegenerative diseases and injuries. Scientists identified CNTF’s most active regions based on epitope mapping of neutralizing antibodies to CNTF.

This led to the development of Peptide 6, made of 11 amino acids (Ac-VGDGGLFEKKL-NH(2)) and a subsequence of just 4 amino acids called Peptide 6c (Ac-DGGL-NH(2)). These amino acids have been theorized to support hippocampus-dependent learning and memory, increase neurogenesis, and potentially boost neuronal plasticity, as posited in murine models. To improve the stability of the peptide and boost its potential to pass through the blood-brain barrier, the scientists report that they “added adamantane building blocks to the C-terminus or both C- and N-termini of Peptide 6c.” The result is P21, which appears to have the potential to mimic the action of CNTF by activating the CNTF receptor complex and downstream signaling pathways, possibly leading to enhanced cognition, increased proliferation, and neuronal differentiation of adult hippocampal progenitors in murine models. This innovative design underscores the precision-engineered nature of P21 peptide, making it a valuable asset for advanced neuroscience research.

4. Mechanism of Action and Research Applications

The mechanism of action for P21 peptide is centered on its ability to activate the CNTF receptor complex and subsequent downstream signaling pathways, mimicking the biological effects of endogenous CNTF. This activation is hypothesized to promote neuronal survival, enhance neurogenesis, and support synaptic plasticity, particularly in the hippocampus, a region critical for learning and memory. Researchers are investigating P21 for its potential in models of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, as well as in studies of traumatic brain injury and stroke.

Its enhanced stability and ability to potentially cross the blood-brain barrier, attributed to the adamantane building blocks, make P21 a promising candidate for exploring novel neuroprotective strategies. The P21 peptide’s influence on neuronal differentiation and proliferation of adult hippocampal progenitors further highlights its relevance in understanding and potentially addressing cognitive decline. Ongoing research aims to fully characterize its molecular interactions and evaluate its efficacy in various preclinical models, contributing to the development of new therapeutic approaches for neurological disorders.

5. About the Brand

[1] is dedicated to providing high-quality research compounds for scientific exploration. With a commitment to purity and rigorous testing, we ensure that our products meet the exacting standards required for advanced laboratory studies. Our mission is to support the scientific community with reliable and well-characterized peptides, facilitating groundbreaking discoveries and advancements in various fields of research.

6. Frequently Asked Questions (FAQ)

Q1: What is P21 peptide?

P21 peptide is a synthetic peptide designed to mimic the neurotrophic activity of ciliary neurotrophic factor (CNTF), studied for its potential neuroprotective and cognitive-enhancing effects in research models.

Q2: How does P21 peptide mimic CNTF?

P21 peptide is engineered to activate the CNTF receptor complex and its downstream signaling pathways, thereby emulating the neurotrophic and neuroprotective actions of natural CNTF.

Q3: Is P21 peptide suitable for human use?

No, P21 peptide is strictly for research use only. It is not approved for human or animal consumption, clinical use, or therapeutic application, and should only be handled by qualified professionals in a laboratory setting.

Q4: What are the research applications of P21 peptide?

P21 peptide is primarily studied in research for its potential in models of neurodegenerative diseases, cognitive enhancement, and recovery from neurological injuries, making it a subject of interest in neuroscience.

Q5: What is the recommended P21 peptide dosage for research?

Specific P21 peptide dosage protocols are determined by individual research studies and should be established by the lead researcher based on the experimental design and desired outcomes. Always adhere to strict laboratory guidelines and ethical considerations when determining dosage for in-vitro research.

Q6: Where can I buy P21 peptide for research?

P21 peptide for sale is available from specialized suppliers of research chemicals. Ensure that any supplier adheres to strict quality control and provides comprehensive product information for scientific use.

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P21 (5mg)

Essential P21 Peptide: Proven 5mg for Neuroprotective Research

Table of Contents

1. Introduction to P21 Peptide

2. Product Details

3. Understanding P21: A Synthetic CNTF Mimetic

4. Mechanism of Action and Research Applications

5. About the Brand

6. Frequently Asked Questions (FAQ)

Reviews

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P21 (5mg)

Essential P21 Peptide: Proven 5mg for Neuroprotective Research

Table of Contents

1. Introduction to P21 Peptide

2. Product Details

3. Understanding P21: A Synthetic CNTF Mimetic

4. Mechanism of Action and Research Applications

5. About the Brand

6. Frequently Asked Questions (FAQ)

Reviews

Be the first to review “P21 (5mg)” Cancel reply

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