Semax Peptide – Advanced Cognitive Support & Neuroprotective Nootropic
Elevate your research capabilities with Semax, a synthetic heptapeptide meticulously engineered to support cognitive function, neuroprotection, and neurological recovery.
Product Overview
Semax Peptide
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Sequence: Met-Glu-His-Phe-Pro-Gly-Pro (MEHFPGP)
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Molecular Formula: C₃₇H₅₁N₉O₁₀S
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Molecular Weight: 813.92 g/mol
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CAS Number: 80714-61-0
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Purity: >99% (HPLC)
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Form: Lyophilized Powder
Advanced Cognitive Enhancement
Semax represents a breakthrough in cognitive enhancement research. This ACTH(4-10) analog was specifically designed to retain the neuroactive properties of its parent molecule while eliminating hormonal side effects . The result is a focused nootropic peptide that supports:
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Memory Consolidation & Recall: Research indicates Semax promotes hippocampal neurogenesis through BDNF upregulation
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Enhanced Focus & Attention: Modulates dopaminergic and serotonergic neurotransmitter systems
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Mental Clarity & Processing Speed: Supports optimal neurotransmitter balance for improved cognitive performance

Comprehensive Neuroprotection
Semax demonstrates significant neuroprotective potential through multiple mechanisms:
BDNF & Neurotrophic Support
Administration of Semax produces notable elevation in Brain-Derived Neurotrophic Factor (BDNF), essential for neuronal survival, synaptic plasticity, and the formation of new neural connections . This supports long-term brain health and cognitive resilience.
Antioxidant & Anti-inflammatory Action
Semax functions as an effective neuroprotectant by:
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Reducing oxidative damage through antioxidant properties
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Decreasing neuroinflammation by modulating pro-inflammatory cytokine production
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Protecting neurons from ischemic and traumatic injury
Cerebral Blood Flow Enhancement
By improving cerebral circulation, Semax ensures optimal oxygen and nutrient delivery to brain cells, supporting peak mental performance and metabolic waste removal .
Research-Backed Applications
Semax has been extensively studied for various neurological applications:
Ischemic Stroke & Cerebrovascular Conditions
Registered and clinically used in Russia for ischemic stroke treatment, Semax reduces neurological deficits and infarct volume . Studies demonstrate its ability to accelerate recovery through neuroprotection and cognitive restoration.
Neurodegenerative Disease Research
Emerging evidence highlights Semax’s potential in Alzheimer’s disease research. In animal models, Semax:
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Improved cognitive function
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Reduced amyloid plaque accumulation in cortex and hippocampus
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Demonstrated potential for therapeutic strategies in neurodegenerative conditions
Cognitive Disorders
Research explores Semax applications in ADHD, dementia, and encephalopathy, showing promise for cognitive enhancement in various neuropsychological contexts .
Traumatic Brain Injury & Neuroregeneration
Semax supports recovery following brain injury by:
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Promoting neuronal survival through NGF and NT-3 stimulation
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Facilitating functional recovery through multiple signaling pathways
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Supporting Schwann cell interaction and nerve regeneration
Mechanism of Action
Semaglutide operates through a sophisticated network of neurochemical pathways:
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Neurotransmitter Modulation: Regulates dopamine and serotonin levels, supporting mood stability, attention, and cognitive performance
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BDNF/TrkB Pathway Activation: Upregulates BDNF and its receptor TrkB, crucial for neuronal survival, growth, and synaptic plasticity
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Metal Ion Interaction: Forms stable complexes with copper(II) ions, inhibiting Aβ:Cu²⁺ complex formation and interfering with amyloid fibrillogenesis
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Anti-inflammatory & Antioxidant Effects: Modulates NF-κB and Nrf2 pathways involved in cellular stress responses and inflammation
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Gene Expression Regulation: Corrects gene expression patterns disrupted by ischemia, modulating immune and neuro-signaling pathways
Specifications & Handling
Storage Instructions:
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Store lyophilized peptide at -20°C or below
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Protect from moisture and light
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Refer to handling guidelines for reconstitution protocols
Solubility:
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Slightly soluble in aqueous solutions (1.5 g/L at 25°C)
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TFA salt form enhances aqueous solubility
Quality Assurance
Our Semax peptide is:
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Synthetically manufactured with high purity (>99% HPLC)
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Delivered as lyophilized powder for maximum stability
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Available with comprehensive analytical data
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Strictly for research and laboratory use
Legal & Regulatory Information
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Not for human consumption – For research purposes only
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Manufactured and tested under strict quality control standards
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Please consult your local regulations regarding peptide research compounds
Order Semax Peptide Today
Advance your neuroscience research with premium-grade Semax peptide. Our rigorous quality standards ensure you receive a product you can trust for consistent, reproducible results.
For research use only. Not for diagnostic or therapeutic use in humans.




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